lipophilia

[US]/ˌlɪpəˈfɪliə/
[UK]/ˌlɪpəˈfɪliə/

Translation

n. med affinitet for fedt eller lipider; tendens til at akkumulere fedt

Phrases & Collocations

lipophilia study

lipofilie-studie

lipophilia research

lipofilie-forskning

lipophilia analysis

lipofilie-analyse

lipophilia effect

lipofilie-effekt

lipophilia test

lipofilie-test

Example Sentences

the new candidate shows high lipophilia, which explains its rapid accumulation in adipose tissue.

Den nye kandidat viser høj lipofilie, hvilket forklarer dens hurtige akkumulering i fedtvæv.

low lipophilia in the formulation limits its ability to cross the blood‑brain barrier.

Lav lipofilie i formuleringen begrænser dens evne til at passere blod-hjerne-barrieren.

increasing lipophilia by adding a long alkyl chain improved the membrane permeability of the drug.

At øge lipofilien ved at tilføje en lang alkylkæde forbedrede lægernes membranpermeabilitet.

the assay measures lipophilia through the partition coefficient between octanol and water.

Det testmål måler lipofilie gennem partionskoefficienten mellem oktanol og vand.

a moderate lipophilia profile is often desirable for oral drugs to balance absorption and clearance.

En moderat lipofilprofil er ofte ønskværdig for oral medicin for at balancere optagelse og udførelse.

scientists correlate the compound's lipophilia with its efficacy in targeting lipid‑rich tumors.

Videnskabsmænd korrelerer stoffets lipofilie med dets effektivitet i at målrette lipidrige tumorer.

the lipophilia index was used to rank the series of analogues for further development.

Lipofilieindekset blev brugt til at rangere rækken af analoger til yderligere udvikling.

during the optimization process, decreasing lipophilia reduced the drug's off‑target binding to plasma proteins.

Under optimeringsprocessen reducerede en lavere lipofilie lægernes afmærkning til plasmaproteiner.

the intrinsic lipophilia of the molecule determines its passive diffusion across cellular membranes.

Molekylens intrinsiske lipofilie bestemmer dets passive diffusion gennem cellemembraner.

high lipophilia can also increase the risk of accumulation in non‑target fatty tissues.

En høj lipofilie kan også øge risikoen for akkumulering i ikke-målrettede fedtvæv.

regulatory agencies consider lipophilia as a key parameter when evaluating the safety profile of novel compounds.

Regulatoriske myndigheder vurderer lipofilie som en vigtig parameter ved vurdering af sikkerhedsprofilen for nye forbindelser.

the lipophilia measurement was performed using a high‑throughput shake‑flask method.

Lipofilie-målingen blev udført ved brug af en høj-egenskabs ryst-flaskemetode.

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