mitophagy

dysregulated mitophagy contributes to the development of neurodegenerative diseases.

researchers have identified key regulators of mitophagy in mammalian cells.

the pink1/parkin pathway is essential for mitophagy induction.

mitophagy deficiency leads to the accumulation of damaged mitochondria.

pharmacological agents can promote mitophagy to protect against cellular damage.

impaired mitophagy has been linked to cardiovascular diseases.

the relationship between mitophagy and cellular homeostasis is complex.

aging is associated with a decline in mitophagy efficiency.

exercise can enhance mitophagy in skeletal muscle.

mitophagy plays a crucial role in maintaining mitochondrial dna integrity.

defective mitophagy results in increased oxidative stress.

scientists are exploring therapeutic strategies to modulate mitophagy.