heregulins

[US]/hɪˈrɛɡjʊlɪnz/
[UK]/hɪˈrɛɡjʊlɪnz/

Translation

n.A family of growth factors that bind to HER/erbB receptors (particularly HER3 and HER4), acting as ligands to activate signaling pathways involved in cell proliferation, differentiation, and survival.

Phrases & Collocations

using heregulins

heregulins help

heregulins reduce

heregulins contain

heregulins improve

heregulins support

heregulins boost

heregulins enhance

heregulins work

natural heregulins

Example Sentences

heregulins are signaling proteins that bind to her receptors on cell surfaces.

the heregulin family includes multiple isoforms with distinct functions.

heregulin expression regulates cell growth and differentiation processes.

scientists study how heregulins activate intracellular signaling cascades.

the heregulin-her axis plays crucial roles in embryonic development.

mutations affecting heregulin binding can disrupt normal cellular functions.

heregulin levels can be measured using specialized immunoassay techniques.

the therapeutic potential of heregulins remains an active research area.

heregulins promote cell survival through pi3k-akt pathway activation.

researchers discovered that heregulins also influence neuronal development.

the overexpression of heregulins has been observed in certain cancer types.

heregulin signaling involves dimerization of her receptor tyrosine kinases.

different heregulin isoforms show varying affinities for her receptors.

the biological activity of heregulins depends on their specific domains.

experimental models demonstrate that heregulins can induce morphological changes.

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