osteoclasts

osteoclasts are responsible for bone resorption during remodeling.

excessive osteoclast activity can lead to osteoporosis.

researchers are investigating ways to inhibit osteoclast formation.

the rankl/rank/opg pathway regulates osteoclast differentiation.

bisphosphonates are drugs that target and inhibit osteoclast function.

osteoclast precursors reside in the bone marrow environment.

the fusion of osteoclast precursors forms mature osteoclasts.

osteoclast activity is crucial for bone fracture healing.

increased osteoclast numbers are observed in some cancers.

macrophages and osteoclasts share some molecular mechanisms.

the differentiation of osteoclasts is a tightly regulated process.